Michael M. Lell, M.D.

Professor of Radiology Senior radiologist and deputy director of the Department of Radiology – Expert in Cardiovascular Imaging, Dose Reduction

Curriculum vitae

All posts of Michael M. Lell, M.D.

Imaging the Parasinus Region with a Third-Generation Dual Source CT and the Effect of Tin Filtration on Image Quality and Dose.

posted by Michael M. Lell, M.D. | Jul 13, 2017
Michael M. Lell, M.D.

CT is the imaging technique of choice in the evaluation of midface trauma or inflammatory disease. We performed a systematic evaluation of scan protocols to optimize image quality and radiation exposure on third-generation dual-source CT. Read more

Third-generation dual-source 70-kVp chest CT angiography with advanced iterative reconstruction in young children: image quality and radiation dose reduction platform.

posted by Michael M. Lell, M.D. | Oct 25, 2016
Michael M. Lell, M.D.

Objective: To evaluate image quality and radiation dose of high-pitch second- and third-generation dual-source chest CT angiography and to assess the effects of different levels of advanced modeled iterative reconstruction (ADMIRE) in newborns and children. Read more

Contrast volume reduction using third generation dual source CT for the evaluation of patients prior to transcatheter aortic valve implantation platform.

posted by Michael M. Lell, M.D. | Oct 10, 2016
Michael M. Lell, M.D.

Objective: Chronic renal failure is common in patients referred for transcatheter aortic valve implantation (TAVI). CT angiography is recommended and provides crucial information prior to TAVI. We evaluated the feasibility of a reduced contrast volume protocol for pre-procedural CTimaging. Read more

Low-Dose CT of Paranasal Sinuses: Minimizing X-Ray Exposure with Spectral Shaping.

posted by Michael M. Lell, M.D. | Sep 2, 2016
Michael M. Lell, M.D.

Objective: This study’s aim was to investigate dose and image quality of tin filtration at 100 kV for pre-operative planning in low-dose paranasal CT imaging in a large patient cohort. Read more

Prospectively ECG-triggered high-pitch coronary angiography with third-generation dual-source CT at 70 kVp tube voltage: feasibility, image quality, radiation dose, and effective of iterative reconstruction.

posted by Michael M. Lell, M.D. | Mar 23, 2016
Michael M. Lell, M.D.

Objective: We evaluated feasibility, image quality (IQ), and radiation dose of coronary CTA using a third-generation dual-source CT system capable of producing 450 mAs tube current at 70 kVp tube voltage. Read more

Performance of today’s dual energy CT and future multi energy CT in virtual non-contrast imaging and in iodine quantification: A simulation.

posted by Michael M. Lell, M.D. | Jan 21, 2016
Michael M. Lell, M.D.

To study the performance of different dual energy computed tomography (DECT) techniques, which are available today, and future multi energy CT (MECT) employing novel photon counting detectors in an image-based material decomposition task. Read more

Case: Volume perfusion CT in liver metastases

posted by Michael M. Lell, M.D. | Dec 18, 2015
Michael M. Lell, M.D.

Volume perfusion CT in liver metastases Read more

Case: Dual Energy CT: identifying both uric acid and calcium oxalate kidney stones

posted by Michael M. Lell, M.D. | Oct 9, 2015
Michael M. Lell, M.D.
  • Tabelle

Dual Energy CT: identifying both uric acid and calcium oxalate kidney stones Read more

Optimizing contrast media injection protocols in state-of-the art CT angiography

posted by Michael M. Lell, M.D. | Aug 12, 2015
Michael M. Lell, M.D.

The optimization of CM injection protocols is mandatory to achieve state-of the art CTA at low kilovolt and can reduce CM doses to patients. Read more

Automated tube voltage selection in thoracoabdominal CT at high pitch using a third-generation dual-source scanner: image quality and radiation dose performance

posted by Michael M. Lell, M.D. | Jul 29, 2015
Michael M. Lell, M.D.

Automated tube voltage adaptation combined with high-pitch protocols allows for a substantial radiation dose reduction while substantially increasing the image quality, even at large-volume exposure. Read more

Dual energy CT: how well can pseudo-monochromatic imaging reduce metal artifacts?

posted by Michael M. Lell, M.D. | Jul 15, 2015
Michael M. Lell, M.D.

Pseudo-monochromatic imaging is able to reduce beam hardening, scatter, and metal artifacts in some cases but it cannot remove them. Read more

Imaging the Parasinus Region with a Third-Generation Dual-Source CT and the Effect of Tin Filtration on Image Quality and Radiation Dose

posted by Michael M. Lell, M.D. | Jul 1, 2015
Michael M. Lell, M.D.

CT is the imaging technique of choice in the evaluation of midface trauma or inflammatory disease. We performed a systematic evaluation of scan protocols to optimize image quality and radiation exposure. High resolution 3D imaging can be performed at a dose level comparable to conventional radiography. Read more

Interobserver variability of CT angiography for evaluation of aortic annulus dimensions prior to transcatheter aortic valve implantation (TAVI)

posted by Michael M. Lell, M.D. | Feb 13, 2015
Michael M. Lell, M.D.

Contrast-enhanced multidetector CT allows 3-D assessment of aortic annulus dimensions. Only limited data exist about its interobserver variability. Read more

Contrast medium application in pediatric high-pitch cardiovascular CT angiography: manual or power injection?

posted by Michael M. Lell, M.D. | Jan 30, 2015
Michael M. Lell, M.D.

There is considerable controversy about the administration of contrast medium in infants and small children, with either a power injector or a manual (hand) injection. Read more

Dose reduction in CT of the chest: image quality of iterative reconstructions at a 50% radiation dose compared to filtered back projection at a 100% radiation dose

posted by Michael M. Lell, M.D. | Jan 23, 2015
Michael M. Lell, M.D.

The aim of this study was to evaluate the potential of iterative reconstruction (IR) in chest CT to reduce radiation exposure. Read more

Accuracy of prospectively ECG-triggered very low-dose coronary dual-source CT angiography using iterative reconstruction for the detection of coronary artery stenosis: comparison with invasive catheterization

posted by Michael M. Lell, M.D. | Dec 3, 2014
Michael M. Lell, M.D.

Raw data-based IR significantly improves image quality in very low-dose prospectively ECG-triggered coronary dual-source CTA when compared with standard reconstruction using FBP. Read more

Dose Reduction in CT of the Chest: Image Quality of Iterative Reconstructions at a 50% Radiation Dose Compared to Filtered Back Projection at a 100% Radiation Dose

posted by Michael M. Lell, M.D. | Jun 4, 2014
Michael M. Lell, M.D.

The aim of this study was to evaluate the potential of iterative reconstruction (IR) in chest CT to reduce radiation exposure. Read more

Carotid CTA: Radiation Exposure and Image Quality with the Use of Attenuation-Based, Automated Kilovolt Selection

posted by Michael M. Lell, M.D. | Apr 2, 2014
Michael M. Lell, M.D.

The attenuation-based, kilovolt selection algorithm enables a dose reduction of >30% in carotid artery CTA while maintaining contrast-to-noise ratio and subjective image quality at adequate levels. Read more

Frequency split metal artefact reduction in pelvic CT

posted by Michael M. Lell, M.D. | Mar 25, 2014
Michael M. Lell, M.D.

NMAR, FSLIMAR and FSNMAR have the potential to improve image quality in patients with artefacts from metal hardware and to improve the diagnostic accuracy of CT of the organs of the pelvis. Read more

Attenuation-based automatic kilovolt (kV)-selection in CT of the chest: effects on radiation exposure and image quality

posted by Michael M. Lell, M.D. | Feb 24, 2014
Michael M. Lell, M.D.

The attenuation based kV-selection algorithm enables relevant dose reduction (~27%) in chest-CT while keeping image quality parameters at high levels. Read more

Stent evaluation in low-dose coronary CT angiography: Effect of different iterative reconstruction settings

posted by Michael M. Lell, M.D. | Feb 19, 2014
Michael M. Lell, M.D.

Aim of this study was to test whether different IR settings have a clinically relevant influence on image quality and on the diagnostic accuracy of low-dose CT angiography in patients with a stent. Read more

A method to determine suitable fluoroscopic projections for transcatheter aortic valve implantation by CT

posted by Michael M. Lell, M.D. | Feb 7, 2014
Michael M. Lell, M.D.

We developed and validated a simple method to predict suitable fluoroscopic projections on the basis of cardiac CT datasets. Read more

Patient-specific predictors of image noise in coronary CT angiography

posted by Michael M. Lell, M.D. | Feb 4, 2014
Michael M. Lell, M.D.

We aimed to find a patient-specific predictor of image noise to determine the use of reduced tube voltage. Read more

Low-dose dual-source CT angiography with iterative reconstruction for coronary artery stent evaluation

posted by Michael M. Lell, M.D. | Jan 24, 2014
Michael M. Lell, M.D.

The purpose of this study was to evaluate the image quality and diagnostic accuracy of very low-dose DSCT angiography for the evaluation of coronary stents. Read more

Image quality of ultra-low radiation exposure coronary CTA with an effective dose <0.1 mSv using high-pitch spiral acquisition and raw data-based iterative reconstruction

posted by Michael M. Lell, M.D. | Apr 30, 2013
Michael M. Lell, M.D.

We evaluated the potential of prospectively ECG-triggered high-pitch spiral acquisition with low tube voltage and current in combination with iterative reconstruction to achieve coronary CT angiography with sufficient image quality at an effective dose below 0.1 mSv. Read more

Radiation dose considerations by intra-individual Monte Carlo simulations in dual source spiral coronary CTA with electrocardiogram-triggered tube current modulation and adaptive pitch

posted by Michael M. Lell, M.D. | Mar 20, 2013
Michael M. Lell, M.D.

Objectives To evaluate radiation dose levels in patients undergoing spiral coronary computed tomography angiography (CTA) on a dual-source system in clinical routine. Materials and methods Coronary CTA was performed for 56 patients with electrocardiogram-triggered tube current modulation (TCM) and heart-rate (HR) dependent pitch adaptation. Individual Monte Carlo (MC) simulations were performed for dose … Read more

Normalized metal artifact reduction in head and neck CT

posted by Michael M. Lell, M.D. | Mar 5, 2013
Michael M. Lell, M.D.

We developed a generalized normalization technique for MAR (NMAR) that aims to suppress algorithm-induced artifacts and validated the performance of this algorithm in a clinical trial. Read more

Attenuation-based automatic kilovolt selection in abdominal CT: effects on radiation exposure and image quality

posted by Michael M. Lell, M.D. | Jan 21, 2013
Michael M. Lell, M.D.

We sought to evaluate an attenuation-based fully automated kV-selection and milliampere second-adaption algorithm for CT and to assess radiation dose and image quality in comparison with a standard 120 kV protocol in contrast-enhanced (CE) portal-venous thoracoabdominal imaging. Read more

Carotid CTA with automated bone suppression: a comparative study between dual energy and bone subtraction techniques

posted by Michael M. Lell, M.D. | Aug 1, 2012
Michael M. Lell, M.D.

We sought to compare the performance of fully automated bone removal based on dual energy (DE) and image registration (bone subtraction CTA [BSCTA]) for the supraaortic vasculature. Read more

Cardiac spiral dual-source CT with high pitch: a feasibility study

posted by Michael M. Lell, M.D. | Jun 5, 2012
Michael M. Lell, M.D.

Increase of pitch in spiral CT decreases data acquisition time; DSCT systems provide improved temporal resolution. We evaluated the combination of these two features. Read more

High-pitch electrocardiogram-triggered CT of the chest: initial results

posted by Michael M. Lell, M.D. | Feb 20, 2012
Michael M. Lell, M.D.

We describe a new high-pitch scan mode, which has been developed specifically for low-dose ECG-triggered CTA using DSCT. Read more

Dual energy CTA of the supraaortic arteries: technical improvements with a novel dual source CT system

posted by Michael M. Lell, M.D. | Jan 30, 2012
Michael M. Lell, M.D.

We sought to describe the performance of DE-CTA of the supraaortic vessels with a novel dual source CT system with special emphasis on image quality and post-processing related artifacts. Read more

Radiation exposure and image quality in staged low-dose protocols for coronary dual-source CT angiography: a randomized comparison

posted by Michael M. Lell, M.D. | Jan 3, 2012
Michael M. Lell, M.D.

To evaluate staged low-dose approaches for coronary CT angiography (CTA) in which a standard sequence was added if the low-dose sequence did not allow reliable rule-out of coronary stenosis. Read more

Coronary CTA with a consistent dose below 1 mSv using prospectively electrocardiogram-triggered high-pitch spiral acquisition

posted by Michael M. Lell, M.D. | Dec 20, 2011
Michael M. Lell, M.D.

We evaluated the feasibility and image quality of a new scan mode for coronary computed tomography angiography (CTA) with an effective dose of less than 1 mSv. Read more

Evaluation of coronary stents and stenoses at different heart rates with dual source spiral CT (DSCT)

posted by Michael M. Lell, M.D. | Nov 26, 2011
Michael M. Lell, M.D.

The utilization of dual source computed tomography (DSCT) might improve the visualization of the coronary arteries by imaging at a temporal resolution of 83 milliseconds, independent of heart rate. Read more

Presentation: Pediatric High-Pitch Spiral CT

posted by Michael M. Lell, M.D. | Nov 24, 2011

Flash Spiral CT Imaging without breath hold and sedation. Presentation on the occasion of the IPR congress. Read more

Effect of CT scan protocols on x-ray-induced DNA double-strand breaks in blood lymphocytes of patients undergoing coronary CTA

posted by Michael M. Lell, M.D. | Nov 18, 2011
Michael M. Lell, M.D.

To compare in vivo DNA lesions induced during helical and sequential coronary CTA and to evaluate the effect of CT parameters on double-strand break (DSB) levels. Read more

High-pitch spiral CT: effect on image quality and radiation dose in pediatric chest CT

posted by Michael M. Lell, M.D. | Nov 10, 2011
Michael M. Lell, M.D.

We evaluated a new, subsecond high-pitch scan mode (HPM), which obviates the need of sedation and to hold the breath. Read more

Dose reduction in abdominal CT: intraindividual comparison of image quality of full-dose standard and half-dose iterative reconstructions with DSCT

posted by Michael M. Lell, M.D. | Nov 3, 2011
Michael M. Lell, M.D.

We sought to evaluate the image quality of iterative reconstruction in image space (IRIS) in half-dose (HD) datasets compared with full-dose (FD) and HD filtered back projection (FBP) reconstruction in abdominal CT. Read more

Detection of coronary artery stenoses by low-dose, prospectively ECG-triggered, high-pitch spiral coronary CT angiography

posted by Michael M. Lell, M.D. | Oct 26, 2011
Michael M. Lell, M.D.

We sought to evaluate the diagnostic accuracy of a new prospectively electrocardiogram (ECG)-triggered high-pitch scan mode for coronary CTA, which allows an effective dose of less than 1 mSv. Read more

High-pitch thoracic CT with simultaneous assessment of coronary arteries: effect of heart rate and heart rate variability on image quality and diagnostic accuracy

posted by Michael M. Lell, M.D. | Oct 18, 2011
Michael M. Lell, M.D.

We sought to evaluate the diagnostic accuracy of a new prospectively electrocardiogram (ECG)-triggered high-pitch scan mode for coronary CTA, which allows an effective dose of less than 1 mSv. Read more




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