A Novel Imaging Technique (X-Map) to Identify Acute Ischemic Lesions Using Noncontrast Dual-Energy CT
We evaluated whether X-map, a novel imaging technique, can visualize ischemic lesions within 20 hours after the onset in patients with acute ischemic stroke, using noncontrast dual-energy computed tomography (DECT).
Material and Methods
Six patients with acute ischemic stroke were included in this study. Noncontrast head DECT scans were acquired with 2 X-ray tubes operated at 80 kV and Sn150 kV between 32 minutes and 20 hours after the onset. Using these DECT scans, the X-map was reconstructed based on 3-material decomposition and compared with a simulated standard (120 kV) computed tomography (CT) and diffusion-weighted imaging (DWI).
The X-map showed more sensitivity to identify the lesions as an area of lower attenuation value than a simulated standard CT in all 6 patients. The lesions on the X-map correlated well with those on DWI. In 3 of 6 patients, the X-map detected a transient decrease in the attenuation value in the peri-infarct area within 1 day after the onset.
The X-map is a powerful tool to supplement a simulated standard CT and characterize acute ischemic lesions. However, the Xmap cannot replace a simulated standard CT to diagnose acute cerebral infarction.
Authors: Noguchi K, Itoh T, Naruto N, Takashima S, Tanaka K, Kuroda S.
Full text available at: J Stroke Cerebrovasc Dis. 2016 Sep 14.